The Impact of Systems Biology on the Digital Patient

Our bioinformatics activities are collaborations between the Biomedical Informatics Lab of the Institute of Computer Science and the Computational Biology Lab of the Institute of Molecular Biology and Biotechnology. The common goal is the data-driven discovery of novel regulatory networks. In most cases, these networks are related to various diseases. One specific focus is the study of the interferon signalling network and its interplay with clinically relevant pathogens such as Cytomegalovirus. In particular, we are developing computational methods to investigate the role in various diseases of a novel class of small regulatory genes called microRNA (miRNA).